Fig. 11. ECG and EGCG are KCNQ-dependent vasorelaxants. All error bars indicate SEM. A: Concentration-response for relaxation of methoxamine-precontracted rat mesenteric artery by epicatechin gallate alone (black) or in the presence of linopirdine (red) (n = 6). B: Concentration-response for relaxation of methoxamine-precontracted rat mesenteric artery by epigallocatechin-3-gallate alone (black) or in the presence of linopirdine (red) (n = 7-8). C: Concentration-response for relaxation of methoxamine-precontracted rat mesenteric artery by epicatechin alone (black) or in the presence of linopirdine (red) (n = 4). D: Scatter plot showing epicatechin gallate LogEC₅₀ values for relaxation of methoxamine-precontracted rat mesenteric artery alone or in the presence of linopirdine as indicated (n = 6). *P<0.05 according to an unpaired Student's t test. E: Scatter plot showing epigallocatechin-3-gallate R_max values for methoxamine-precontracted rat mesenteric artery alone or in the presence of linopirdine as indicated (n = 7-8). **P<0.001 according to an unpaired Student's t test.